This research explores how ChatGPT can enhance vaccine messaging effectiveness for public health departments with limited resources.

Key findings:

• LLM-augmented messaging shows promise in promoting vaccination confidence
• Provides resource-efficient solutions for smaller public health departments
• Helps counter vaccine hesitancy and misinformation barriers
• Demonstrates practical application of AI in public health communication

Why it matters: Public health departments can leverage AI tools to craft more persuasive vaccination messages, potentially increasing uptake rates and improving community health outcomes without requiring specialized expertise.

Working with Large Language Models to Enhance Messaging Effectiveness for Vaccine Confidence