
Bridging Proteins and Language Models
Enabling structure-aware reasoning in protein science with LLMs
ProtTeX introduces a novel approach that enables large language models to understand and edit protein structures, going beyond simple amino acid sequences.
- Developed a structure-aware tokenization system that converts 3D protein structures into text
- Created a structure-in-context learning framework that allows LLMs to reason about and edit proteins
- Achieved superior performance in protein structure prediction and editing compared to existing methods
- Demonstrated practical applications in protein design and functional analysis
This research represents a significant breakthrough for computational biology by allowing AI to truly understand protein structures, potentially accelerating drug discovery and protein engineering efforts.
ProtTeX: Structure-In-Context Reasoning and Editing of Proteins with Large Language Models