Bridging Proteins and Language Models

Bridging Proteins and Language Models

Enabling structure-aware reasoning in protein science with LLMs

ProtTeX introduces a novel approach that enables large language models to understand and edit protein structures, going beyond simple amino acid sequences.

  • Developed a structure-aware tokenization system that converts 3D protein structures into text
  • Created a structure-in-context learning framework that allows LLMs to reason about and edit proteins
  • Achieved superior performance in protein structure prediction and editing compared to existing methods
  • Demonstrated practical applications in protein design and functional analysis

This research represents a significant breakthrough for computational biology by allowing AI to truly understand protein structures, potentially accelerating drug discovery and protein engineering efforts.

ProtTeX: Structure-In-Context Reasoning and Editing of Proteins with Large Language Models

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