This research introduces Ask Patients with Patience (APP), a novel framework to enhance LLMs for medical consultations through grounded reasoning and iterative diagnosis improvement.

• Enables multi-turn medical dialogues with follow-up questions to refine diagnoses
• Translates complex medical terminology into patient-friendly language
• Incorporates medical guidelines for more accurate diagnostic reasoning
• Bridges communication gaps between AI systems and non-medical users

This advancement matters because it transforms LLMs from passive information providers into active diagnostic assistants that can engage patients with appropriate medical questioning while maintaining accessibility—potentially increasing healthcare access and accuracy in telehealth settings.

Ask Patients with Patience: Enabling LLMs for Human-Centric Medical Dialogue with Grounded Reasoning