Prot2Chat introduces a novel framework that overcomes key limitations in protein function prediction by integrating protein representations with natural language processing capabilities.

• Combines sequence and structural information through an early fusion approach
• Enables flexible, natural language interactions with protein data
• Outperforms existing classification-based methods for protein analysis
• Provides a unified platform for protein question-answering tasks

Why it matters: This innovation bridges the gap between complex protein data and human-interpretable analysis, potentially accelerating drug discovery, protein engineering, and fundamental biological research.

Prot2Chat: Protein LLM with Early Fusion of Sequence and Structure