This research demonstrates how content generated by large language models can effectively reduce stigma around opioid use disorder in online communities.

• LLM-generated content significantly decreased stigmatizing attitudes toward opioid use disorder and medication-assisted treatment
• The study validates AI as a powerful tool for health communication interventions
• Findings show AI can create empathetic, educational content that changes negative perceptions
• Results highlight the potential for technology-assisted approaches to address public health challenges

This research has significant implications for medical professionals seeking innovative ways to combat stigma that creates barriers to treatment and recovery for those with substance use disorders.

Exposure to Content Written by Large Language Models Can Reduce Stigma Around Opioid Use Disorder in Online Communities