DOLA (Dose Optimization Language Agent) is an autonomous system that integrates LLaMa3.1 with commercial treatment planning software to optimize radiotherapy plans for prostate cancer patients.

• Addresses inter-planner variability and subjective decision-making in treatment planning
• Utilizes chain-of-thought processing to make complex optimization decisions
• Prioritizes patient privacy with robust data protection measures
• Demonstrates potential for improved efficiency in clinical workflows

This innovation matters because it can standardize treatment quality, reduce planning time, and ultimately improve patient outcomes while maintaining strict privacy standards in medical settings.

Autonomous Radiotherapy Treatment Planning Using DOLA: A Privacy-Preserving, LLM-Based Optimization Agent