The DOLA (Dose Optimization Language Agent) system represents a breakthrough in autonomous radiotherapy planning, leveraging LLaMa3.1 LLM to enhance treatment efficiency while protecting patient privacy.

• Autonomous optimization of radiotherapy treatment plans reducing manual workload
• Direct integration with commercial treatment planning systems
• Privacy-preserving architecture ensuring patient data protection
• Chain-of-thought processing for transparent decision-making

This innovation addresses critical challenges in cancer treatment, including reducing inter-planner variability, eliminating subjective decision-making, and potentially expanding access to high-quality radiotherapy planning in resource-limited settings.

Autonomous Radiotherapy Treatment Planning Using DOLA: A Privacy-Preserving, LLM-Based Optimization Agent